Pharmaceutical microbiology Essay Example | Topics and Well Written Essays - 1000 words

Pharmaceutical microbiology - Essay Example Development and maintenance of a sterile compounding are complete with sterilized equipment and supplies. Aseptic technique is a means of manipulating sterile products without contaminating them. Proper use of a LAH and strict aseptic technique are the most important factors in preventing the contamination of sterile products Contamination is a basic in introduction of antibiotic resulting into need for aseptic techniques .the techniques is designed to prevent access of the drug by the unnecessary substances and this is a risk associated with contamination which may include; The air, air that is not sterilize may contain bacteria e.g. micrococci, bacillus and clostridium. And these are pathogenic and may access the drug during production; the staff involved may also risk the drug by introducing bacteria especially which may eject droplets into the air compromising the properties of the drug. The skin may be contaminated especially most of the hand s by handling non sterilize product which are not sterilize and machines and these may then transfer the pathogen to the drug during preparation risking its purity. The clothing used during aseptic preparation should be sterilized less they risk the status of the products they produce, before starting the production, the laundry should be done to eliminate the dust that may be carried into the preparation room and the sleeve should be rolled above the elbow so that they do not pick any foreign bodies from surfaces which are not clean. Before taking any procedure in preparation in the production room through aseptic, the surfaces of the working benches should be sterilized using a bactericidal solution to minimize the risk that the drug may be exposed to. Sealing reduces the risk of the drug to contamination, used of fused ampules is much preferred which are the sterilized after sealing ,the product is then expected to remain